EPA Studies in Libby to take Years

Posted by richald Monday, December 14, 2009 0 comments

Libby, Montana has become an icon in the story of the destructive power of asbestos. The W.R. Grace Company’s vermiculite mine located there operated until 1990 extracting vermiculite ore that was contaminated with asbestos. The health impact on the community has been long established by a long history of asbestos cancer and other asbestos related diseases occurring at a high rate. The prospect of asbestos liability claims for related illnesses and deaths drove W.R. Grace into bankruptcy.

The federal government has provided emergency medical care for residents in the area along with other support needed by a community suffering from widespread illness and displacement. The EPA has declared the mine a federal Superfund Site, one of the nation’s top priorities for the cleanup of toxic waste. At that point, it seems, things have begun to slow down.

The frustration boiled over Tuesday at a meeting in Libby where federal scientists were long on technical explanations but short on answers about how toxic Libby’s unusual form of asbestos really is. “What is a safe dose for Libby?” Lerah Parker asked. “I want to know when it’s safe to bring my family back to our property.” EPA toxicologist Dave Berry had no answer for her. According to Montana’s Daily InterLake, Ten years ago Parker and her husband, Mel, were forced off their land — the former vermiculite screening plant for W.R. Grace & Co. — and had to close down a thriving nursery business.

Berry was on hand to explain the federal agency’s risk-assessment process for the Libby Superfund site. Risk assessments have been completed for Operable Units 1 and 2, but assessments for other portions of the Superfund site continue. They include the city of Libby, the vermiculite mine site, the former Stimson lumber mill, railroad and highway corridors and the nearby community of Troy.

The federal government mobilizes cleanup efforts once the risk assessment shows one death per 10,000 people, Berry explained. A local writer pointed out that the population of the Libby area is about 10,000 and at least 31 residents have already died from mesothelioma.

Complicating the issue from the EPA’s viewpoint is the fact that the type of asbestos contained in the vermiculite ore was relatively rare in industrial use. Risk assessments for Libby amphibole asbestos — a more deadly needle-sharp fiber than the less-toxic and more common chrysotile asbestos — are based largely on old science, EPA officials admitted.

But the astonishing statistic in all of this is that the epidemiology and toxicology studies of Libby asbestos are a minimum of five years away from being completed. Libby residents feel that the EPA is ignoring other epidemiological studies of asbestos and engaging in an academic exercise that ignores the evidence, provided by the hundreds of local residents who have asbestosis and other related respiratory afflictions.

The Washington Post reports today on a former exhibit specialist who work at the National Air and Space Museum during his 28 year career with the Smithsonian Institute and who developed asbestosis as a result. Richard Pullman, 54, has settled a lawsuit with the institution for $233,000, according to records obtained by The Post this month from the Department of Labor under the Freedom of Information Act.

Pullman said he frequently sawed and drilled into interior walls to install and update exhibits for more than 25 years. In 2008, he and other workers were told for the first time that the walls contained asbestos, Pullman said. Asbestosis, a lung disease linked to breathing asbestos fibers, was diagnosed in Pullman by his physicians.

This story broke in March, causing Smithsonian Secretary G. Wayne Clough to order an investigation of the facility’s potential asbestos exposure by an outside consultant. The Institute chose to make the report public because the Post had obtained a record of the lawsuit settlement during their document search.

The report’s findings include the observation that the Smithsonian failed to keep a complete record on asbestos-containing material. Workers often did not have adequate information on the location of asbestos or how to work around it, according to the report. Workplace exposure has subsequently become an important issue at the museum, in large part due to the news stories.

Pullman asserted that he was often assigned the task of drilling through walls to mount exhibits when those walls contained asbestos or asbestos joint compound. Joint compound used for finishing out wallboard was a widely used asbestos product through the 1970s. In 1992 another consultant retained by the museum reported that there was 1 to 5 percent asbestos in the joint compound used in two dozen Air and Space museum rooms. A level above 1 percent is supposed to trigger worker-safety requirements; the Smithsonian has acknowledged that worker warnings rarely occurred.

The documents obtained by the Post show a pattern of non-concern on the part of Smithsonian’s management. The 2007 plans to replace the electrical system misled contractors about the amount of asbestos found in the walls. The museum maintained asbestos levels were less than one percent, at that time. Pullman collected dust samples from the museum that showed high levels of asbestos content.

A high-visibility, high interest criminal trial has opened in Italy over asbestos exposure that killed at least 2,200 former employees of the firm Eternit. On trial are one wealthy Swiss national and an 88 year old member of Belgian nobility, both of whom worked with the company or served on the board at some point in the 1970s.

The company in question is the Italian firm Eternit, a corporation that turned out products made from cement reinforced with asbestos fiber. The case has developed intense interest in Europe; on the trial’s opening day the courtroom had to utilize the space of four courtrooms because of the presence of 400 asbestos victims, family members, and 150 attorneys.

The victims – who died of mesothelioma or fell sick over at least the past four decades – were either Eternit workers or residents of towns where the firm’s four Italian plants were based. The two defendants are accused of negligence because there were no warnings to employees or anyone else about the potential hazards of asbestos. The plants were all closed in 1986.

According to various European news agencies these defendants were high executives with the company and ignored the developing awareness of health problems associated with inhaled asbestos fibers. The number of deaths attributed to these four plants suggests that not only workplace exposure but widespread distribution of asbestos dust to surrounding areas occurred during the years of plant operation.

There has been only one federal prosecution of asbestos company executives in the United States – similar charges of negligence filed against six W.R. Grace executives – and that case ended in acquittal in early 2009. Nevertheless W.R. Grace has been in bankruptcy for years due to asbestos claims and has established a $2 billion trust fund to reimburse former employees. The record of civil litigation in these Eternit cases is not clear, but the public anger over perceived negligence may be the precursor for substantial asbestos litigation yet to come.

asbestosnews.com

A jury in Baltimore Circuit Court has found Scapa Dryers, Inc. liable in the asbestos-related mesothelioma and lung cancer of former paper worker Carl Saville. In the 1960s and 1970s, Saville was exposed to asbestos-containing dryer felts produced by Scapa as well as pipe, cement and block insulation installed by insulation contractor Wallace & Gale. The jury awarded $1.718 million to Saville, who has waited for this retrial since the 2003 trial and verdict for the plaintiff was overturned on appeal.

During the mid 1960s and 1970s, he worked on drying machines in a paper plant which utilized Scapa-manufactured dryer felts containing chrysotile asbestos. Wallace & Gale, an insulation contractor to the paper mill where Saville worked, was added as a new defendant in the retrial after its emergence from bankruptcy. In 2002, Saville was diagnosed with lung cancer and a malignant mesothelioma tumor was discovered during the lobectomy. Saville has since gone without cancer recurrence for the past six years.

Mr. Saville is one of the lucky few to have had a case of mesothelioma go into remission. The average survival term for malignant mesothelioma is eighteen months or less after diagnosis. Most plaintiffs in asbestos litigation don’t live long enough to see an appeal completed on the initial verdict.

Scapa Dryers, Inc. manufactured the 200-foot long dryer felts used in Saville’s paper plant. Wallace & Gale is a Baltimore-based manufacturer of sheet metals, fiber sheets and alloy sheets. The company served as an insulation contractor for the installation and repair of several types of asbestos containing insulation at the paper mill where Saville worked.

Another couple that sued Scapa Dryer Fabrics and an additional co-defendant was awarded $10.2 million in November due to workplace exposure in the Crown Zellerbach paper mill in Camus, WA. Henry Barbin worked as a pulp tester, and paper tester at between 1968 and 2001. Exposed to asbestos fibers from dryer fabrics for almost 40 years, he was diagnosed with mesothelioma cancer in 2006.

Henry and Geraldine Barbin’s asbestos lawsuit claimed that the asbestos dryer fabrics were defectively designed and failed to carry warnings about the dangers of asbestos exposure. Henry Barabin was awarded $700,000 for medical expenses, lost income and household services and $8 million in non-economic damages for pain and suffering. Geraldine Barbin was awarded another $1.5 million for her loss of consortium claim.

asbestosnews.com

Asbestos: The Silent KillerAsbestos was one of the most common industrial materials put to use in the twentieth century. It has also proven to be one of the most lethal, as inhaling asbestos fibers can lead to a wide range of pulmonary problems such as asthma and asbestosis - and can also be the direct cause of mesothelioma.

What is mesothelioma? It is a lethal cancer that attacks the membranes around the lungs, the heart and the abdominal cavity. Mesothelioma cancer of the lungs is by far the most common form. Perhaps its most unusual characteristic is that mesothelioma diagnosis usually occurs decades after the initial exposure to asbestos.

It takes years for the asbestos fibers to work their way into those membranes; after an extended presence they begin to cause fluid accumulation and tumor development. However the first mesothelioma symptoms are such afflictions as a persistent cough or shortness of breath - symptoms that are often mistaken for evidence of more common lung problems, which delays the mesothelioma diagnosis even further.

http://www.asbestosnews.com/

chemotherapy effectiveness in mesothelioma

Posted by richald Thursday, December 3, 2009 0 comments

A recent mesothelioma study compared three different methods of evaluating chemotherapy effectiveness in mesothelioma and found one method to be more effective than the others.

Experts in the field of mesothelioma will attest that measuring tumor response to chemotherapy is especially difficult because tumors of this cancer follow a non-spherical growth pattern along the pleural surface of the lung, which is challenging to evaluate. An accurate method for measuring tumor response is important to all cancer treatment as it helps doctors assess the treatment’s ability to reduce the size and growth of the tumor. Thus, finding a successful method of measuring chemotherapeutic effect in mesothelioma is very important to improving mesothelioma treatment.

Considering the added challenge of measuring the non-spherical mesothelioma tumors, finding an accurate method of measuring tumors is crucial to improving patient prognosis and survival. Presently, the average life span of a mesothelioma patient is four to 18 months after diagnosis. Improvements in trimodality therapy (using three different treatments, including surgery, chemotherapy and radiation) are increasing survival rates among some mesothelioma patients, offering hope to those diagnosed with this aggressive cancer.

The researchers stated, “There is no ‘gold standard’ technique for tumor measurement in MPM [malignant pleural mesothelioma]. Bi-dimensional response criteria established by the World Health Organization (WHO) have been used for many years. However, WHO criteria are poorly suited to the growth pattern of MPM and insufficient for some patients.”

Another method, known as modified RECIST (Response Evaluation Criteria in Solid Tumor), has become the standard method for mesothelioma tumor analysis. But investigators of this method have identified weaknesses that have resulted in over-classification of tumors. Additionally, interpretation of the data can vary greatly from doctor to doctor, yet another variable that compromises the method’s accuracy.

The study proposed “that indefinable shapes can be represented as spheres with defined volumes, thereby allowing three-dimensional evaluation of the chemotherapy response.” Results from the study supported the researchers’ three-dimensional method over the WHO and RECIST methods.

The researchers concluded, “When considering the non-spherical growth pattern of tumor and the difficulty in choosing target lesion, the most reliable approach for evaluation of tumor response in mesothelioma might be direct measurement of tumor volume change in three dimensions as completely as possible… We recommend the use of our method for determining the chemotherapy response in mesothelioma cases. ”

Additional information on mesothelioma and chemotherapy may be found through the Mesothelioma Center.

An article in the Journal of Medical Case Reports recently reported a case of pleural mesothelioma in a 73-year-old man in which the complete disappearance of the tumor was achieved through both traditional and alternative therapies.

Authors of the article report that “a pleurectomy was performed, and as expected, the tumor locally relapsed with increasing chest pain. However, the symptoms suddenly improved while the tumor was apparently reduced, and spontaneous tumor regression was initially considered. The patient confessed that he had self-administered a mushroom extract with alternative parasympathetic nerve stimulation therapy [a type of acupuncture] thereafter.” Throughout a 29-month follow-up, the complete disappearance of the tumor was clinically attained with continuing self-treatment by the patient.

Malignant mesothelioma is an aggressive cancer caused almost exclusively by asbestos exposure. Patients typically survive four to 18 months after diagnosis. Improved survival rates are sometimes seen in some patients who undergo trimodality therapy combining surgery, chemotherapy and radiation. Not all patients can undergo all three traditional treatments, and instead opt for just chemotherapy or radiation or a combination of the two.

Sometimes, mesothelioma treatment can be complimented by alternative therapies such as the mushroom extract used by the patient in this case report. Following a pleurectomy, postoperative intrathoracic chemotherapy with Carboplatin and systemic chemotherapy with Gemcitabine, the patient orally self-administered a mushroom extract and received acupuncture in another hospital.

The mushroom extract contained the edible mushroom known as Agaricus blazei Murill Kyowa (ABMK), which is native to Brazil and cultivated in Japan for medicinal use. The mushroom has been used to treat arteriosclerosis, hepatitis, diabetes, dermatitis and cancer. According to the Memorial Sloan-Kettering Cancer Center Web site, studies on ABMK have revealed its immunomodulatory (helps to regulate the immune system), antitumor and antimutagenic properties. Sloan-Kettering also reports that “a recent randomized study showed that oral administration of Agaricus extract improved the natural killer cell activity and quality of life in gynecological cancer patients undergoing chemotherapy.”

The acupuncture the patient underwent is an alternative parasympathetic nerve stimulation therapy that is reported to have possible immune-modulation (the potential to either stimulate or suppress the immune system). The patient experienced two weeks of high fever and then his general condition distinctly improved. Four months after the alternative therapies, the relapsed tumor had significantly decreased and eventually completely disappeared.

Although another completely separate local tumor appeared many months after the initial tumor disappeared, the patient was alive and continuing the previously beneficial alternative therapies of ABMK extract and acupuncture.

Additional information on mesothelioma and other survivor stories may be found through the Mesothelioma Center.

Shipyard workers and crew members were routinely exposed to asbestos-containing materials during the World War II era and through the 1980s. At the time, asbestos was thought to be an ideal material to use because of its resistance to corrosion and ability to withstand high temperatures and fires.

However, the side effects of asbestos exposure are still being felt today as past shipyard workers and Navy veterans are still developing asbestos-related diseases. The ships that were built during World War II were heavily contaminated with asbestos. Areas and materials that commonly contained the hazardous mineral were boiler rooms, sleeping quarters, pipes and parts that needed to be insulated.

Due to close quarters and heavy use of ships during the war, materials that contained toxic asbestos fibers were routinely being damaged and replaced. Crew members would often bump into the walls and pipes that contained asbestos insulation, which unfortunately led to the dispersion of asbestos fibers into the air. In addition, the overuse and age of a ship would often contribute to asbestos exposure because the natural deterioration of materials could also release asbestos fibers.

Throughout the 20th century, shipyards across the nation employed hundreds of thousands of workers. Those that were heavily exposed to asbestos usually included welders, painters and machinists on the ships.

Many of the workers did not have access to proper preventative gear to protect them from exposure. In fact, most were completely unaware that exposure to asbestos carried any risk at all. Today, asbestos is a hazardous material that is known to cause several forms of serious disease, including lung cancer, asbestosis and malignant mesothelioma.

Mesothelioma is a rare type of cancer that is almost exclusively caused by asbestos exposure. Many shipyard employees have either passed away or have been diagnosed with the disease and more are expected as the latency period associated with mesothelioma can range from 20 to 50 years.

Diagnosing this cancer is particularly difficult, as symptoms often resemble those of more common illnesses. In many cases, patients are diagnosed at a time when the cancer has already reached the latest stages of development, leaving them with limited treatment options.

Those who may have experienced asbestos exposure from the shipyard industry should receive regular checkups from a doctor that can recognize signs of exposure. Receiving an early diagnosis gives a person a much greater chance of having a positive effect from treatment.

Additional information about mesothelioma and asbestos exposure may be found through the Mesothelioma Center.

Asbestos Exposure

Posted by richald 0 comments

Asbestos Exposure

Asbestos ExposureAsbestos exposure is the single known cause of mesothelioma. Inhaled or ingested asbestos fibers may cause an inflammation of internal tissue and disrupt organ function which leads to the development of the disease. Asbestos products were used extensively throughout the 20th century in a wide variety of applications. Many of these products were responsible for asbestos exposure sustained by both the individuals who manufactured the products as well as those who used them at commercial and industrial jobsites including shipyards, refineries, power plants, steel plants and more. Several asbestos companies continued to produce these products even after they were known to be hazardous and harmful to workers and their families. Those who have become sick because of exposure to these products may now be eligible for financial compensation if they were wrongfully exposed.

Asbestos was also used at many New York jobsites including Ground Zero and the former World Trade Center site. Common asbestos exposure sites in New York include the Brooklyn Navy Yard, Todd Shipyard, and the Con Edison power plant in New York City.